Journal: Lab on a Chip
Article Title: 3D modelling of pulmonary arterial stenosis and endothelial dysfunction in CTEPH †
doi: 10.1039/d5lc00300h
Figure Lengend Snippet: Wall shear stress in semi-circular channels simulated with water. Computational fluid dynamics (CFD) results showing wall shear stress (WSS) at the top and bottom of the semi-circular in the control (A–C), 30% stenosis (D–F), 60% stenosis (G–I) and 80% stenosis (J–L) models. Colour scales at the top of the images in (A)–(H) represent a WSS range between 0.0–2.0 Pa (0.0–20 dyn cm −2 ), while in (J and K) the scale ranges from 0.0–18.1 Pa (0.0–181 dyn cm −2 ). In (C, F, I and L) the x axis indicates the different regions of the channel: upstream (U; 7 mm), stenosis (S; 11 mm), post-stenotic dilatation (PSD; 13.5 mm), downstream 1 (D1; 18 mm) and downstream 2 (D2; 22.5 mm). All simulations were performed in CFX (Ansys, Inc.), using an inlet velocity of 60.2 mm s −1 (0.5 L h −1 ) and outlet pressure of 0.097 kPa.
Article Snippet: All results files were post-processed and analysed in CFD POST (Ansys, Inc.).
Techniques: Shear, Control